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講題: A forest-Based approach in Association Study
演講者：柳清地 教授(Department of Biostatistics Boston University School of Public Health, USA)
Abstract :Multiple genes, gene-by-gene interactions, and gene-by-environment interactions are believed to underline most complex diseases. However, such interactions are difficult to identify. While there have been recent successes in identifying genetic variants for complex diseases, it still remains difficult to identify gene-gene and gene-environment interactions. To overcome this difficulty, we propose a forest-based approach and a concept of variable importance. The proposed approach is demonstrated by simulation study for its validity and illustrated by a real data analysis for its use. Analyses of both real data and simulated data based on published genetic models show the effectiveness of our approach.
時間：2010年12月21日(星期二) 14：00 ∼ 17：00
地點：推廣大樓3樓9313室
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